Animal alternative test & Skin clinical trials
Introduction
The KTR Animal alternatives & Clinical center is the only authorized testing and certification body in Korea that evaluates the safety and efficacy of cosmetics, medical care, biomaterials, and chemical products Using non-animal testing and conducts skin testing at the same time.
KTR has established an Animal alternatives & Clinical center in KTR Healthcare Institute in November 2016 to help Korean companies advance into the domestic and international markets, according to the latest global ban on animal testing. Our tests consist of nonclinical testing areas for Specialized animal alternative testing and efficacy trials, and skin clinical trials for safety and efficacy of cosmetic ingredients and products. We provide highly reliable data using state-of-the-art facilities and equipment.
You can get an one-stop service that includes non-clinical testing, skin clinical trials, material development, product manufacturing and export through KTR
Korea's first Integrated service of Animal alternative test and clinical trials as an official testing and certification body
- - Regarding cosmetics, chemical substances and medical equipments, we conduct Animal alternative tests and in-vitro efficacy test in reference to the notification and guidelines of the Ministry of Environment, Ministry of Food and Drug Safety and Rural Development Administration.
- - Animal alternatives test in reference to OECD guideline and GLP test regulations
1. Safety assessment - Safety evaluation service using alternative tests
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Alternative skin irritation test
Skin irritation test using Reconstructed human skin model
Skin corrosion test using Reconstructed human skin model
Skin corrosion test using Membrane Barrier test method
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Phototoxic test
Phototoxic test using cell line
- 3T3 NRU assay -
Alternative skin sensitization test
Local lymph node assay (BrdU-ELISA)
Peptide reactivity test (kDPRA)
Human Cell Line Activation Test (h-CLAT)
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Alternative eye irritation test
Bovine Corneal Opacity and Permeability (BCOP) assay
Hen's egg test-chorioallantoic membrane (HET-CAM) assay
Eye irritation test using Reconstructed human cornea model
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In vitro skin absorption test
Skin absorption test using Franz Cell
2. In-vitro efficacy test
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Brightening efficacy test
Melanin formation inhibition test
Tyrosinase activity inhibition test
DOPA oxidation inhibition test
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Cytotoxicity
MTT assay
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Wrinkle improvement test
Collagenase activity inhibition test
Collagen synthesis assay
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Antioxidation test
DPPH free radical scavenging activation test
ABTS Radical Scavenging Assay
Superoxide Dismutase(SOD) Activity Assay
Total Polyphenols Content Assay
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Other efficacy tests
Hair loss-related efficacy test (hFDPC proliferation assay,‘5α-reductase assay)
